CN: 11-456
Species: Ruminant, Sheep
Specimen:
Heart
Shown:
Serous atrophy of fat in an animal with Johne's disease
Pathology:
Serous atrophy of fat
Negative plane of energy e.g. starvation, anorexia, cachexia, GI parasitism, etc.
Gross Appearance:
Watery and gelatinous fat
References:
Jubb, Kennedy and Palmer's Pathology of Domestic Animals
Etiology:
Johne's Disease
Causative Agent:
Mycobacterium avium subspecies paratuberculosis (MAP)
Species Affected:
Any domestic ruminant
Clinical Signs:
- Affects cattle 2 years of age or older, profuse diarrhea with progressive emaciation.
- In sheep, goats, and other ruminants, diarrhea may not be seen.
- Infected animals can appear healthy for months to years.
Pathology:
Ingestion and uptake in the Peyer's patches of the lower small intestine --> infection of macrophages and lymph nodes.
References:
Collins, Merck Veterinary Manual
